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TITLE: Preclinical evaluation of RNAi as a treatment for transthyretin-mediated amyloidosis  Full Text
AUTHORS: Butler, JS; Chan, A; Costelha, S; Fishman, S; Willoughby, JLS; Borland, TD; Milstein, S; Foster, DJ; Goncalves, P; Chen, QM; Qin, J; Bettencourt, BR; Sah, DW; Alvarez, R; Rajeev, KG; Manoharan, M; Fitzgerald, K; Meyers, RE; Nochur, SV; Saraiva, MJ ; Zimmermann, TS; ...More
PUBLISHED: 2016, SOURCE: AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, VOLUME: 23, ISSUE: 2
INDEXED IN: Scopus WOS CrossRef: 77
IN MY: ORCID
32
TITLE: Transthyretin participates in beta-amyloid transport from the brain to the liver-involvement of the low-density lipoprotein receptor-related protein 1?  Full Text
AUTHORS: Mobina Alemi; Cristiana Gaiteiro; Carlos Alexandre Ribeiro; Luis Miguel Santos; Joao Rodrigues Gomes; Sandra Marisa Oliveira ; Pierre Olivier Couraud; Babette Weksler; Ignacio Romero; Maria Joao Saraiva ; Isabel Cardoso;
PUBLISHED: 2016, SOURCE: SCIENTIFIC REPORTS, VOLUME: 6
INDEXED IN: Scopus WOS CrossRef: 73
IN MY: ORCID
33
TITLE: Transthyretin provides trophic support via megalin by promoting neurite outgrowth and neuroprotection in cerebral ischemia  Full Text
AUTHORS: Gomes, JR; Nogueira, RS; Vieira, M; Santos, SD; Ferraz Nogueira, JP; Relvas, JB ; Saraiva, MJ ;
PUBLISHED: 2016, SOURCE: Cell Death and Differentiation, VOLUME: 23, ISSUE: 11
INDEXED IN: Scopus CrossRef: 39
IN MY: ORCID
34
TITLE: Polymer-doxycycline conjugates as fibril disrupters: An approach towards the treatment of a rare amyloidotic disease  Full Text
AUTHORS: Conejos Sanchez, I; Cardoso, I; Oteo Vives, M; Romero Sanz, E; Paul, A; Sauri, AR; Morcillo, MA; Saraiva, MJ ; Vicent, MJ;
PUBLISHED: 2015, SOURCE: JOURNAL OF CONTROLLED RELEASE, VOLUME: 198
INDEXED IN: Scopus WOS CrossRef: 27
IN MY: ORCID
35
TITLE: Protective Role of Anakinra Against Transthyretin-Mediated Axonal Loss and Cell Death in a Mouse Model of Familial Amyloidotic Polyneuropathy
AUTHORS: Goncalves, NP; Teixeira Coelho, M; Saraiva, MJ ;
PUBLISHED: 2015, SOURCE: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, VOLUME: 74, ISSUE: 3
INDEXED IN: Scopus WOS CrossRef: 6
IN MY: ORCID
36
TITLE: Transthyretin Induces Insulin-like Growth Factor I Nuclear Translocation Regulating Its Levels in the Hippocampus  Full Text
AUTHORS: Vieira, M; Gomes, JR; Saraiva, MJ ;
PUBLISHED: 2015, SOURCE: MOLECULAR NEUROBIOLOGY, VOLUME: 51, ISSUE: 3
INDEXED IN: Scopus WOS CrossRef: 20
IN MY: ORCID
37
TITLE: Gene therapy approach to FAP: in vivo influence of T119M in TTR deposition in a transgenic V30M mouse model  Full Text
AUTHORS: Batista, AR; Gianni, D; Ventosa, M; Coelho, AV; Almeida, MR ; Sena Esteves, M; Saraiva, MJ ;
PUBLISHED: 2014, SOURCE: GENE THERAPY, VOLUME: 21, ISSUE: 12
INDEXED IN: Scopus WOS CrossRef: 8
IN MY: ORCID
38
TITLE: Gene therapy approach to FAP: In vivo influence of T119M in TTR deposition in a transgenic V30M mouse model (Gene Therapy advance online publication (2014) 10.1038/gt.2014.86))
AUTHORS: Batista, AR; Gianni, D; Ventosa, M; Coelho, AV; Almeida, MR; Sena Esteves, M; Saraiva, MJ ;
PUBLISHED: 2014, SOURCE: Gene Therapy, VOLUME: 21, ISSUE: 12
INDEXED IN: Scopus
IN MY: ORCID
39
TITLE: Glial cells in familial amyloidotic polyneuropathy
AUTHORS: Nádia Pereira Gonçalves; Susete Costelha; Maria João Saraiva ;
PUBLISHED: 2014, SOURCE: Acta Neuropathologica Communications, VOLUME: 2, ISSUE: 1
INDEXED IN: Scopus CrossRef: 11
IN MY: ORCID
40
TITLE: Interleukin-1 signaling pathway as a therapeutic target in transthyretin amyloidosis  Full Text
AUTHORS: Goncalves, NP; Vieira, P; Saraiva, MJ ;
PUBLISHED: 2014, SOURCE: AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, VOLUME: 21, ISSUE: 3
INDEXED IN: Scopus WOS CrossRef: 31
IN MY: ORCID
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