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Pedro Henrique Gomes Soares

AuthID: R-001-VM7

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Confirmed Publications: 29

11

TITLE: Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases
AUTHORS: Chavarria, D ; Da Silva, O; Benfeito, S ; Barreiro, S; Garrido, J; Cagide, F ; Soares, P ; Remiao, F ; Brazzolotto, X; Nachon, F; Oliveira, PJ; Dias, J; Borges, F ;
PUBLISHED: 2021, SOURCE: ANTIOXIDANTS, VOLUME: 10, ISSUE: 2

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12

TITLE: Design of novel monoamine oxidase-B inhibitors based on piperine scaffold: Structure-activity-toxicity, drug-likeness and efflux transport studies Full Text
AUTHORS: Daniel Chavarria ; Carlos Fernandes; Vera Silva; Catia Silva; Eva Gil Martins; Pedro Soares ; Tiago Silva; Renata Silva; Fernando Remiao ; Paulo J Oliveira; Fernanda Borges ;
PUBLISHED: 2020, SOURCE: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 185

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13

TITLE: Isothiazolinone Biocides: Chemistry, Biological, and Toxicity Profiles Full Text
AUTHORS: Vania Silva; Catia Silva; Pedro Soares ; Manuela M Garrido; Fernanda Borges ; Jorge Garrido;
PUBLISHED: 2020, SOURCE: MOLECULES, VOLUME: 25, ISSUE: 4

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14

TITLE: Disruption of mitochondrial function as mechanism for anti-cancer activity of a novel mitochondriotropic menadione derivative Full Text
AUTHORS: Jose Teixeira; Ricardo Amorim; Katia Santos; Pedro Soares ; Sandipan Datta; Gino A Cortopassi; Teresa L Serafim; Vilma A Sardao; Jorge Garrido ; Fernanda Borges ; Paulo J Oliveira;
PUBLISHED: 2018, SOURCE: TOXICOLOGY, VOLUME: 393

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15

TITLE: Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase: Structure-Activity Relationships Leading to the Chemical Probe (2S,4R)-1-((S)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (VH298) Full Text
AUTHORS: Soares, P ; Gadd, MS; Frost, J; Galdeano, C; Ellis, L; Epemolu, O; Rocha, S; Read, KD; Ciulli, A;
PUBLISHED: 2018, SOURCE: Journal of Medicinal Chemistry, VOLUME: 61, ISSUE: 2

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16

TITLE: Thioamide substitution to probe the hydroxyproline recognition of VHL ligands Full Text
AUTHORS: Soares, P ; Lucas, X; Ciulli, A;
PUBLISHED: 2018, SOURCE: Bioorganic and Medicinal Chemistry, VOLUME: 26, ISSUE: 11

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17

TITLE: Development of a Mitochondriotropic Antioxidant Based on Caffeic Acid: Proof of Concept on Cellular and Mitochondrial Oxidative Stress Models Full Text
AUTHORS: Jose Teixeira; Fernando Cagide ; Sofia Benfeito ; Pedro Soares ; Jorge Garrido; Ines Baldeiras; Jose A Ribeiro ; Carlos M Pereira ; Antonio F Silva ; Paula B Andrade ; Paulo J Oliveira; Fernanda Borges ;
PUBLISHED: 2017, SOURCE: JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 60, ISSUE: 16

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18

TITLE: Discovery of neurotrophic agents based on hydroxycinnamic acid scaffold Full Text
AUTHORS: Razieh Hosseini; Fatemeh Moosavi; Hamid Rajaian; Tiago Silva; Diogo M E Magalhaes e Silva; Pedro Soares ; Luciano Saso; Najmeh Edraki; Ramin Miri; Fernanda Borges ; Omidreza Firuzi;
PUBLISHED: 2016, SOURCE: CHEMICAL BIOLOGY & DRUG DESIGN, VOLUME: 88, ISSUE: 6

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19

TITLE: Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition
AUTHORS: Frost, J; Galdeano, C; Soares, P ; Gadd, MS; Grzes, KM; Ellis, L; Epemolu, O; Shimamura, S; Bantscheff, M; Grandi, P; Read, KD; Cantrell, DA; Rocha, S; Ciulli, A;
PUBLISHED: 2016, SOURCE: Nature Communications, VOLUME: 7, ISSUE: 1

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20

TITLE: Synthesis of 6-aryl/heteroaryl-4-oxo-4H-chromene-2-carboxylic ethyl ester derivatives Full Text
AUTHORS: Carlos Fernandes; Pedro Soares ; Alexandra Gaspar ; Daniel Martins; Ligia R Gomes; John N Low; Fernanda Borges ;
PUBLISHED: 2016, SOURCE: TETRAHEDRON LETTERS, VOLUME: 57, ISSUE: 27-28

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