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TITLE: miRNA-31 Improves Cognition and Abolishes Amyloid-β Pathology by Targeting APP and BACE1 in an Animal Model of Alzheimer’s Disease
AUTHORS: Ana Teresa Barros-Viegas; Vítor Carmona; Elisabete Ferreiro; Joana Guedes; Ana Maria Cardoso; Pedro Cunha; Luís Pereira de Almeida ; Catarina Resende de Oliveira; João Pedro de Magalhães; João Peça; Ana Luísa Cardoso;
PUBLISHED: 2020, SOURCE: Molecular Therapy - Nucleic Acids, VOLUME: 19
INDEXED IN: CrossRef: 1
62
TITLE: Mitochondrial and Redox Modifications in Huntington Disease Induced Pluripotent Stem Cells Rescued by CRISPR/Cas9 CAGs Targeting
AUTHORS: Lopes, C; Tang, Y; Anjo, SI; Manadas, B; Onofre, I; de Almeida, LP ; Daley, GQ; Schlaeger, TM; Rego, ACC;
PUBLISHED: 2020, SOURCE: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, VOLUME: 8
INDEXED IN: Scopus WOS CrossRef: 25
63
TITLE: Neurofilaments in spinocerebellar ataxia type 3: blood biomarkers at the preataxic and ataxic stage in humans and mice  Full Text
AUTHORS: Wilke, C; Haas, E; Reetz, K; Faber, J; Garcia Moreno, H; Santana, MM; van de Warrenburg, B; Hengel, H; Lima, M; Filla, A; Durr, A; Melegh, B; Masciullo, M; Infante, J; Giunti, P; Neumann, M; de Vries, J; de Almeida, LP ; Rakowicz, M; Jacobi, H; Schule, R; Kaeser, SA; Kuhle, J; Klockgether, T; Schols, L; Barro, C; Hubener Schmid, J; Synofzik, M; ...More
PUBLISHED: 2020, SOURCE: EMBO MOLECULAR MEDICINE, VOLUME: 12, ISSUE: 7
INDEXED IN: Scopus WOS CrossRef: 71
64
TITLE: Neuropeptide Y Enhances Progerin Clearance and Ameliorates the Senescent Phenotype of Human Hutchinson-Gilford Progeria Syndrome Cells
AUTHORS: Aveleira, CA; Ferreira Marques, M; Cortes, L; Valero, J; Pereira, D; Pereira de Almeida, L ; Cavadas, C;
PUBLISHED: 2020, SOURCE: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, VOLUME: 75, ISSUE: 6
INDEXED IN: Scopus WOS CrossRef: 14
65
TITLE: Protocol for the Characterization of the Cytosine-Adenine-Guanine Tract and Flanking Polymorphisms in Machado-Joseph Disease Impact on Diagnosis and Development of Gene-Based Therapies
AUTHORS: Lopes, SM; Faro, R; Lopes, MM; Onofre, I; Mendonca, N; Ribeiro, J; Januario, C; Nobre, RJ; de Almeida, LP ;
PUBLISHED: 2020, SOURCE: JOURNAL OF MOLECULAR DIAGNOSTICS, VOLUME: 22, ISSUE: 6
INDEXED IN: Scopus WOS CrossRef: 1
66
TITLE: Simple and Fast SEC-Based Protocol to Isolate Human Plasma-Derived Extracellular Vesicles for Transcriptional Research
AUTHORS: Gaspar, LS; Santana, MM; Henriques, C; Pinto, MM; Ribeiro Rodrigues, TM; Girao, H ; Nobre, RJ; de Almeida, LP ;
PUBLISHED: 2020, SOURCE: Molecular Therapy - Methods and Clinical Development in MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, VOLUME: 18
INDEXED IN: Scopus WOS CrossRef: 26 Handle
67
TITLE: The blood-brain barrier is disrupted in Machado-Joseph disease/spinocerebellar ataxia type 3: evidence from transgenic mice and humanpost-mortemsamples
AUTHORS: Lobo, DD; Nobre, RJ; Miranda, CO; Pereira, D; Castelhano, J; Sereno, J; Koeppen, A; Castelo Branco, M; de Almeida, LP ;
PUBLISHED: 2020, SOURCE: ACTA NEUROPATHOLOGICA COMMUNICATIONS, VOLUME: 8, ISSUE: 1
INDEXED IN: Scopus WOS CrossRef: 17
68
TITLE: Trehalose alleviates the phenotype of Machado-Joseph disease mouse models  Full Text
AUTHORS: Santana, MM; Paixao, S; Cunha Santos, J; Silva, TP; Trevino Garcia, A; Gaspar, LS; Nobrega, C; Nobre, RJ; Cavadas, C; Greif, H; de Almeida, LP ;
PUBLISHED: 2020, SOURCE: JOURNAL OF TRANSLATIONAL MEDICINE, VOLUME: 18, ISSUE: 1
INDEXED IN: Scopus WOS CrossRef: 23
69
TITLE: Blood-brain barrier dysfunction as a neuropathological feature in Machado-Joseph Disease: results from human and mouse samples
AUTHORS: Diana Lobo; Rui Nobre; Catarina Miranda; Dina Pereira; João Castelhano; José Sereno; Miguel Castelo-Branco; Luís De Almeida ;
PUBLISHED: 2019, SOURCE: Frontiers in Cellular Neuroscience, VOLUME: 13
INDEXED IN: CrossRef
70
TITLE: Cordycepin activates autophagy through AMPK phosphorylation to reduce abnormalities in Machado-Joseph disease models
AUTHORS: Marcelo, A; Brito, F; Carmo Silva, S; Matos, CA; Alves Cruzeiro, J; Vasconcelos Ferreira, A; Koppenol, R; Mendonca, L; de Almeida, LP ; Nobrega, C;
PUBLISHED: 2019, SOURCE: HUMAN MOLECULAR GENETICS, VOLUME: 28, ISSUE: 1
INDEXED IN: Scopus WOS CrossRef: 37
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