Maria Manuel Duque Vieira Marques dos Santos
AuthID: R-000-NFH
21
TITLE: Identification of tetracyclic lactams as NMDA receptor antagonists with potential application in neurological disorders
AUTHORS: Espadinha, M; Viejo, L; Lopes, RMRM; Herrera Arozamena, C; Molins, E; dos Santos, DJVA; Goncalves, L; Rodriguez Franco, MI; de los Rios, C; Santos, MMM;
PUBLISHED: 2020, SOURCE: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 194
AUTHORS: Espadinha, M; Viejo, L; Lopes, RMRM; Herrera Arozamena, C; Molins, E; dos Santos, DJVA; Goncalves, L; Rodriguez Franco, MI; de los Rios, C; Santos, MMM;
PUBLISHED: 2020, SOURCE: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 194
22
TITLE: Potency and Selectivity Optimization of Tryptophanol-Derived Oxazoloisoindolinones: Novel p53 Activators in Human Colorectal Cancer
AUTHORS: Barcherini, V; Almeida, J; Lopes, EA; Wang, M; Silva, DME; Mori, M; Wang, SM; Saraiva, L ; Santos, MMM;
PUBLISHED: 2020, SOURCE: CHEMMEDCHEM, VOLUME: 16, ISSUE: 1
AUTHORS: Barcherini, V; Almeida, J; Lopes, EA; Wang, M; Silva, DME; Mori, M; Wang, SM; Saraiva, L ; Santos, MMM;
PUBLISHED: 2020, SOURCE: CHEMMEDCHEM, VOLUME: 16, ISSUE: 1
23
TITLE: PPIs as therapeutic targets for anticancer drug discovery: the case study of MDM2 and BET bromodomain inhibitors
AUTHORS: Margarida Espadinha; Stuart J Conway; Maria M.M Santos;
PUBLISHED: 2020, SOURCE: Small Molecule Drug Discovery
AUTHORS: Margarida Espadinha; Stuart J Conway; Maria M.M Santos;
PUBLISHED: 2020, SOURCE: Small Molecule Drug Discovery
24
TITLE: Optimizing the oxazoloisoindolinone family: Identification and biological evaluation of a potent and selective indole-based p53 activator in human colorectal cancer
AUTHORS: Valentina Barcherini; Joana Almeida; Elizabeth Lopes; Mi Wang; Diogo Magalhães e Silva; Mattia Mori; Shaomeng Wang; Lucília Saraiva; Maria M M Santos;
PUBLISHED: 2020, SOURCE: Proceedings of 6th International Electronic Conference on Medicinal Chemistry
AUTHORS: Valentina Barcherini; Joana Almeida; Elizabeth Lopes; Mi Wang; Diogo Magalhães e Silva; Mattia Mori; Shaomeng Wang; Lucília Saraiva; Maria M M Santos;
PUBLISHED: 2020, SOURCE: Proceedings of 6th International Electronic Conference on Medicinal Chemistry
25
TITLE: A Novel Small Molecule p53 Stabilizer for Brain Cell Differentiation
AUTHORS: Amaral, JD; Silva, D; Rodrigues, CMP; Sola, S; Santos, MMM;
PUBLISHED: 2019, SOURCE: FRONTIERS IN CHEMISTRY, VOLUME: 7, ISSUE: JAN
AUTHORS: Amaral, JD; Silva, D; Rodrigues, CMP; Sola, S; Santos, MMM;
PUBLISHED: 2019, SOURCE: FRONTIERS IN CHEMISTRY, VOLUME: 7, ISSUE: JAN
26
TITLE: SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma Full Text
AUTHORS: Sara Gomes; Bartolomeo Bosco; Joana B Loureiro; Helena Ramos; Liliana Raimundo; Joana Soares; Nair Nazareth; Valentina Barcherini; Lucilia Domingues; Carla Oliveira; Alessandra Bisio; Silvano Piazza; Matthias R Bauer; Joao P Bras; Maria Ines Almeida; Celia Gomes; Flivio Reis; Alan R Fersht; Alberto Inga; Maria M M Santos; ...More
PUBLISHED: 2019, SOURCE: CANCERS, VOLUME: 11, ISSUE: 8
AUTHORS: Sara Gomes; Bartolomeo Bosco; Joana B Loureiro; Helena Ramos; Liliana Raimundo; Joana Soares; Nair Nazareth; Valentina Barcherini; Lucilia Domingues; Carla Oliveira; Alessandra Bisio; Silvano Piazza; Matthias R Bauer; Joao P Bras; Maria Ines Almeida; Celia Gomes; Flivio Reis; Alan R Fersht; Alberto Inga; Maria M M Santos; ...More
PUBLISHED: 2019, SOURCE: CANCERS, VOLUME: 11, ISSUE: 8
27
TITLE: Small Molecules Targeting Mutant P53: A Promising Approach for Cancer Treatment
AUTHORS: Elizabeth A Lopes; Sara Gomes; Lucilia Saraiva ; Maria M M Santos;
PUBLISHED: 2019, SOURCE: CURRENT MEDICINAL CHEMISTRY, VOLUME: 26, ISSUE: 41
AUTHORS: Elizabeth A Lopes; Sara Gomes; Lucilia Saraiva ; Maria M M Santos;
PUBLISHED: 2019, SOURCE: CURRENT MEDICINAL CHEMISTRY, VOLUME: 26, ISSUE: 41
28
TITLE: An Update on MDMX and Dual MDM2/X Inhibitors
AUTHORS: Espadinha, M; Barcherini, V; Lopes, EA; Santos, MMM;
PUBLISHED: 2018, SOURCE: CURRENT TOPICS IN MEDICINAL CHEMISTRY, VOLUME: 18, ISSUE: 8
AUTHORS: Espadinha, M; Barcherini, V; Lopes, EA; Santos, MMM;
PUBLISHED: 2018, SOURCE: CURRENT TOPICS IN MEDICINAL CHEMISTRY, VOLUME: 18, ISSUE: 8
29
TITLE: A More Sustainable Process for Preparation of the Muscarinic Acetylcholine Antagonist Umeclidinium Bromide
AUTHORS: Espadinha, M; Lourenco, NMT; Sobral, L; Antunes, R; Santos, MMM;
PUBLISHED: 2018, SOURCE: CHEMMEDCHEM, VOLUME: 13, ISSUE: 19
AUTHORS: Espadinha, M; Lourenco, NMT; Sobral, L; Antunes, R; Santos, MMM;
PUBLISHED: 2018, SOURCE: CHEMMEDCHEM, VOLUME: 13, ISSUE: 19
30
TITLE: Improving anticancer activity towards colon cancer cells with a new p53-activating agent. p53 activation by SYNAP Full Text
AUTHORS: Liliana Raimundo; Margarida Espadinha; Joana Soares; Joana B Loureiro; Marco G Alves ; Maria M M Santos; Lucilia Saraiva ;
PUBLISHED: 2018, SOURCE: BRITISH JOURNAL OF PHARMACOLOGY, VOLUME: 175, ISSUE: 20
AUTHORS: Liliana Raimundo; Margarida Espadinha; Joana Soares; Joana B Loureiro; Marco G Alves ; Maria M M Santos; Lucilia Saraiva ;
PUBLISHED: 2018, SOURCE: BRITISH JOURNAL OF PHARMACOLOGY, VOLUME: 175, ISSUE: 20