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Enzymatic Bioactivation of the Phenolic Nevirapine Metabolites 2-Hydroxy- and 3-Hydroxy-Nevirapine to Quinoid Intermediates: Covalent Adduct Formation with Nitrogen-Based Amino Acids

AuthID
P-00K-AAS

Author(s)

Harjivan, SG

Pinheiro, PF

Martins, IL

Novais, DA

Wanke, R

Santos, PP

Pereira, SA

Beland, FA

Marques, MM

Antunes, AMM

Document Type

Abstract

Year published

2015

Published

in TOXICOLOGY LETTERS, ISSN: 0378-4274

Volume: 238, Issue: 2, Pages: S359-S360 (2)

Conference

51St Congress of the European-Societies-Of-Toxicology (Eurotox), Date: SEP 13-16, 2015, Location: Portuguese Soc Pharmacol, Sect Toxicol, Porto, PORTUGAL, Sponsors: European Soc Toxicol, Host: Portuguese Soc Pharmacol, Sect Toxicol

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Publication Identifiers

DOI: 10.1016/j.toxlet.2015.08.1025

Wos: WOS:000370693801858

Source Identifiers

ISSN: 0378-4274

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Enzymatic Bioactivation of the Phenolic Nevirapine Metabolites 2-Hydroxy- and 3-Hydroxy-Nevirapine to Quinoid Intermediates: Covalent Adduct Formation with Nitrogen-Based Amino Acids

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Enzymatic Bioactivation of the Phenolic Nevirapine Metabolites 2-Hydroxy- and 3-Hydroxy-Nevirapine to Quinoid Intermediates: Covalent Adduct Formation with Nitrogen-Based Amino Acids

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