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Structure-Activity Relationship Studies and Plasmodium Life Cycle Profiling Identifies Pan-Active N-Aryl-3-Trifluoromethyl Pyrido[1,2-A]Benzimidazoles Which Are Efficacious in an in Vivo Mouse Model of Malaria

AuthID
P-00Q-3DX

Author(s)

Mayoka, G

Njoroge, M

Okombo, J

Gibhard, L

Sanches Vaz, M

Fontinha, D

Birkholtz, LM

Reader, J

van der Watt, M

Coetzer, TL

Lauterbach, S

Churchyard, A

Bezuidenhout, B

Egan, TJ

Yeates, C

Wittlin, S

Prudencio, M

Chibale, K

Document Type

Article

Year published

2019

Published

in JOURNAL OF MEDICINAL CHEMISTRY, ISSN: 0022-2623

Volume: 62, Issue: 2, Pages: 1022-1035 (14)

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Publication Identifiers

DOI: 10.1021/acs.jmedchem.8b01769

SCOPUS: 2-s2.0-85059654654

Wos: WOS:000457067600040

Source Identifiers

ISSN: 0022-2623

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Structure-Activity Relationship Studies and Plasmodium Life Cycle Profiling Identifies Pan-Active N-Aryl-3-Trifluoromethyl Pyrido[1,2-A]Benzimidazoles Which Are Efficacious in an in Vivo Mouse Model of Malaria

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Structure-Activity Relationship Studies and Plasmodium Life Cycle Profiling Identifies Pan-Active N-Aryl-3-Trifluoromethyl Pyrido[1,2-A]Benzimidazoles Which Are Efficacious in an in Vivo Mouse Model of Malaria

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