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TITLE: Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens  Full Text
AUTHORS: Behan, FM; Iorio, F; Picco, G; Gonçalves, Emanuel ; Beaver, CM; Migliardi, G; Santos, R; Rao, YH; Sassi, F; Pinnelli, M; Ansari, R; Harper, S; Jackson, DA; Mcrae, R; Pooley, R; Wilkinson, P; van der Meer, D; Dow, D; Buser Doepner, C; Bertotti, A; Trusolino, L; Stronach, EA; Saez Rodriguez, J; Yusa, K; Garnett, MJ; ...More
PUBLISHED: 2019, SOURCE: NATURE, VOLUME: 568, ISSUE: 7753
INDEXED IN: Scopus WOS CrossRef: 286
IN MY: ORCID
12
TITLE: Structural rearrangements generate cell-specific, gene-independent CRISPR-Cas9 loss of fitness effects
AUTHORS: Gonçalves, Emanuel ; Behan, FM; Louzada, S; Arnol, D; Stronach, EA; Yang, FT; Yusa, K; Stegle, O; Iorio, F; Garnett, MJ;
PUBLISHED: 2019, SOURCE: GENOME BIOLOGY, VOLUME: 20, ISSUE: 1
INDEXED IN: Scopus WOS CrossRef: 17
IN MY: ORCID
13
TITLE: Post-translational regulation of metabolism in fumarate hydratase deficient cancer cells  Full Text
AUTHORS: Gonçalves, Emanuel ; Sciacovelli, M; Costa, ASH; Tran, MGB; Johnson, TI; Machado, D; Frezza, C; Saez Rodriguez, J;
PUBLISHED: 2018, SOURCE: METABOLIC ENGINEERING, VOLUME: 45
INDEXED IN: Scopus WOS CrossRef: 5
IN MY: ORCID
14
TITLE: Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting  Full Text
AUTHORS: Iorio, F; Behan, FM; Gonçalves, Emanuel ; Bhosle, SG; Chen, E; Shepherd, R; Beaver, C; Ansari, R; Pooley, R; Wilkinson, P; Harper, S; Butler, AP; Stronach, EA; Saez Rodriguez, J; Yusa, K; Garnett, MJ;
PUBLISHED: 2018, SOURCE: BMC GENOMICS, VOLUME: 19, ISSUE: 1
INDEXED IN: Scopus WOS CrossRef: 29
IN MY: ORCID
15
TITLE: A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines
AUTHORS: Mehmet Gönen; Barbara A Weir; Glenn S Cowley; Francisca Vazquez; Yuanfang Guan; Alok Jaiswal; Masayuki Karasuyama; Vladislav Uzunangelov; Tao Wang; Aviad Tsherniak; Sara Howell; Daniel Marbach; Bruce Hoff; Thea C Norman; Antti Airola; Adrian Bivol; Kerstin Bunte; Daniel Carlin; Sahil Chopra; Alden Deran; Kyle Ellrott; Peddinti Gopalacharyulu; Kiley Graim; Samuel Kaski; Suleiman A Khan; Yulia Newton; Sam Ng; Tapio Pahikkala; Evan Paull; Artem Sokolov; Hao Tang; Jing Tang; Krister Wennerberg; Yang Xie; Xiaowei Zhan; Fan Zhu; Tero Aittokallio; Hiroshi Mamitsuka; Joshua M Stuart; Jesse S Boehm; David E Root; Guanghua Xiao; Gustavo Stolovitzky; William C Hahn; Adam A Margolin; Bahman Afsari; Antti Airola; Tero Aittokallio; Adrian Bivol; Jesse S Boehm; Kerstin Bunte; Daniel Carlin; Yu-Chuan Chang; Tenghui Chen; Zechen Chong; Sahil Chopra; Glenn S Cowley; Alden Deran; Kyle Ellrott; Haitham Elmarakeby; Elana J Fertig; Gonçalves, Emanuel ; Mehmet Gönen; Pinghua Gong; Peddinti Gopalacharyulu; Kiley Graim; Yuanfang Guan; Christoph Hafemeister; William C Hahn; Lenwood Heath; Bruce Hoff; Sara Howell; Alok Jaiswal; Masayuki Karasuyama; Samuel Kaski; Łukasz Kędziorski; Suleiman A Khan; Niraj Khemka; Erh-kan King; Mario Lauria; Mark Liu; Daniel Machado; Hiroshi Mamitsuka; Daniel Marbach; Adam A Margolin; Mateusz Mazurkiewicz; Michael P Menden; Szymon Migacz; Yulia Newton; Sam Ng; Zhi Nie; Thea C Norman; Tapio Pahikkala; Evan Paull; Paurush Praveen; Corrado Priami; Simone Rizzetto; Miguel Rocha; David E Root; Cameron Rudd; Witold R Rudnicki; Julio Saez-Rodriguez; Artem Sokolov; Lei Song; Gustavo Stolovitzky; Joshua M Stuart; Duanchen Sun; Bence Szalai; Hao Tang; Jing Tang; Aviad Tsherniak; Vladislav Uzunangelov; Francisca Vazquez; Tao Wang; Difei Wang; Barbara A Weir; Krister Wennerberg; Ling-yun Wu; Guanghua Xiao; Yang Xie; Jieping Ye; Yuting Ye; Xiaowei Zhan; Wanding Zhou; Fan Zhu; ...More
PUBLISHED: 2017, SOURCE: CELL SYSTEMS, VOLUME: 5, ISSUE: 5
INDEXED IN: Scopus WOS CrossRef: 10
IN MY: ORCID
16
TITLE: Benchmarking substrate-based kinase activity inference using phosphoproteomic data  Full Text
AUTHORS: Hernandez Armenta, C; Ochoa, D; Gonçalves, Emanuel ; Saez Rodriguez, J; Beltrao, P;
PUBLISHED: 2017, SOURCE: BIOINFORMATICS, VOLUME: 33, ISSUE: 12
INDEXED IN: Scopus WOS CrossRef: 26
IN MY: ORCID
17
TITLE: Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells
AUTHORS: Roumeliotis, TI; Williams, SP; Gonçalves, Emanuel ; Alsinet, C; Velasco Herrera, MD; Aben, N; Ghavidel, FZ; Michaut, M; Schubert, M; Price, S; Wright, JC; Yu, L; Yang, M; Dienstmann, R; Guinney, J; Beltrao, P; Brazma, A; Pardo, M; Stegle, O; Adams, DJ; Wessels, L; Saez Rodriguez, J; McDermott, U; Choudhary, JS; ...More
PUBLISHED: 2017, SOURCE: CELL REPORTS, VOLUME: 20, ISSUE: 9
INDEXED IN: Scopus WOS CrossRef: 52
IN MY: ORCID
18
TITLE: System-Wide Quantitative Proteomics of the Metabolic Syndrome in Mice: Genotypic and Dietary Effects  Full Text
AUTHORS: Terfve, C; Sabido, E; Wu, YB; Gonçalves, Emanuel ; Choi, M; Vaga, S; Vitek, O; Saez Rodriguez, J; Aebersold, R;
PUBLISHED: 2017, SOURCE: JOURNAL OF PROTEOME RESEARCH, VOLUME: 16, ISSUE: 2
INDEXED IN: Scopus WOS CrossRef: 6
IN MY: ORCID
19
TITLE: Systematic Analysis of Transcriptional and Post-transcriptional Regulation of Metabolism in Yeast  Full Text
AUTHORS: Gonçalves, Emanuel ; Nakic, ZR; Zampieri, M; Wagih, O; Ochoa, D; Sauer, U; Beltrao, P; Saez Rodriguez, J;
PUBLISHED: 2017, SOURCE: PLOS COMPUTATIONAL BIOLOGY, VOLUME: 13, ISSUE: 1
INDEXED IN: Scopus WOS CrossRef: 25
IN MY: ORCID
20
TITLE: Widespread Post-transcriptional Attenuation of Genomic Copy-Number Variation in Cancer
AUTHORS: Gonçalves, Emanuel ; Fragoulis, A; Garcia Alonso, L; Cramer, T; Saez Rodriguez, J; Beltrao, P;
PUBLISHED: 2017, SOURCE: CELL SYSTEMS, VOLUME: 5, ISSUE: 4
INDEXED IN: Scopus WOS CrossRef: 44
IN MY: ORCID
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