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TITLE: DUAL CTLA4/PD-1 BLOCKADE IMPROVES SURVIVAL FOR REPLICATION-REPAIR DEFICIENT HIGH-GRADE GLIOMAS FAILING SINGLE AGENT PD-1 INHIBITION: AN IRRDC STUDY
AUTHORS: Das, Anirban; Morgenstern, Daniel; Bianchi, Vanessa; Sudhaman, Sumedha; Edwards, Melissa; Stengs, Lucie; Larouche, Valerie; Samuel, David; Van Damme, An; Gass, David; Ziegler, David; Bielack, Stefan; Zelcer, Shayna; Yalon, Michal; Constantini, Shlomi; Sarosiek, Tomasz; Libionka, Witold; Nichols, Kim; De Mola, Rebecca Loret; Bielamowicz, Kevin; Sabel, Magnus; Frojd, Charlotta; Wood, Matthew D.; Sous Migueis, Joana Cristiano; Abongwa, Chenue; Yen, Lee Yi; Stearns, Duncan; Opocher, Enrico; Bhatia, Kanika; Sen, Santanu; Quiroga Cantero, Eduardo; Solano Paez, Palma; Crooks, Bruce; Magimairajan, Vanan; Reddy, Alyssa; Adamski, Jenny; Mason, Gary; Lindhorst, Scott; Aronson, Melyssa; Ertl Wagner, Birgit; Hawkins, Cynthia; Bouffet, Eric; Tabori, Uri; ...More
PUBLISHED: 2022, SOURCE: NEURO-ONCOLOGY, VOLUME: 24
INDEXED IN: WOS
2
TITLE: Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma
AUTHORS: Kumar, R; Smith, KS; Deng, M; Terhune, C; Robinson, GW; Orr, BA; Liu, APY; Lin, T; Billups, CA; Chintagumpala, M; Bowers, DC; Hassall, TE; Hansford, JR; Khuong Quang, DA; Crawford, JR; Bendel, AE; Gururangan, S; Schroeder, K; Bouffet, E; Bartels, U; Fisher, MJ; Cohn, R; Partap, S; Kellie, SJ; McCowage, G; Paulino, AC; Rutkowski, S; Fleischhack, G; Dhall, G; Klesse, LJ; Leary, S; Nazarian, J; Kool, M; Wesseling, P; Ryzhova, M; Zheludkova, O; Golanov, AV; McLendon, RE; Packer, RJ; Dunham, C; Hukin, J; Fouladi, M; Faria, CC; Pimentel, J; Walter, AW; Jabado, N; Cho, YJ; Perreault, S; Croul, SE; Zapotocky, M; Hawkins, C; Tabori, U; Taylor, MD; Pfister, SM; Klimo, P; Boop, FA; Ellison, DW; Merchant, TE; Onar Thomas, A; Korshunov, A; Jones, DTW; Gajjar, A; Ramaswamy, V; Northcott, PA; ...More
PUBLISHED: 2021, SOURCE: JOURNAL OF CLINICAL ONCOLOGY, VOLUME: 39, ISSUE: 7
INDEXED IN: Scopus WOS
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TITLE: Locoregional delivery of CAR T cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma
AUTHORS: Laura K Donovan; Alberto Delaidelli; Sujith K Joseph; Kevin Bielamowicz; Kristen Fousek; Borja L Holgado; Alex Manno; Dilakshan Srikanthan; Ahmed Z Gad; Randy Van Ommeren; David Przelicki; Cory Richman; Vijay Ramaswamy; Craig Daniels; Jonelle G Pallota; Tajana Douglas; Alyssa C M Joynt; Joonas Haapasalo; Carolina Nor; Maria C Vladoiu; Claudia M Kuzan Fischer; Livia Garzia; Stephen C Mack; Srinidhi Varadharajan; Matthew L Baker; Liam Hendrikse; Michelle Ly; Kaitlin Kharas; Polina Balin; Xiaochong C Wu; Lei Qin; Ning Huang; Ana Guerreiro Stucklin; Sorana S Morrissy; Florence M G Cavalli; Betty Luu; Raul Suarez; Pasqualino De Antonellis; Antony Michealraj; Avesta Rastan; Meenakshi Hegde; Martin Komosa; Olga Sirbu; Sachin A Kumar; Zied Abdullaev; Claudia C Faria; Stephen Yip; Juliette Hukin; Uri Tabori; Cynthia Hawkins; Ken Aldape; Mads Daugaard; John M Maris; Poul H Sorensen; Nabil Ahmed; Michael D Taylor; ...More
PUBLISHED: 2020, SOURCE: NATURE MEDICINE, VOLUME: 26, ISSUE: 5
INDEXED IN: Scopus WOS
4
TITLE: Combined genetic and epigenetic alterations of the TERT promoter affect clinical and biological behavior of bladder cancer  Full Text
AUTHORS: Leao, R; Lee, D; Figueiredo, A; Hermanns, T; Wild, P; Komosa, M; Lau, I; Mistry, M; Nunes, NM; Price, AJ; Zhang, C; Lipman, T; Poyet, C; Valtcheva, N; Oehl, K; Coelho, H; Sayyid, R; Gomes, AM; Castro, LPE; Sweet, J; Vinagre, João ; Apolonio, J; Stephens, D; Faleiro, I; Fadaak, K; Richard, PO; Kulkarni, G; Zlotta, AR; Hamilton, RJ; Castelo Branco, P; Tabori, U; ...More
PUBLISHED: 2019, SOURCE: INTERNATIONAL JOURNAL OF CANCER, VOLUME: 144, ISSUE: 7
INDEXED IN: Scopus WOS CrossRef: 16
5
TITLE: Heterogeneity within the PF-EPN-B ependymoma subgroup  Full Text
AUTHORS: Florence M G Cavalli; Jens Martin Huebner; Tanvi Sharma; Betty Luu; Martin Sill; Michal Zapotocky; Stephen C Mack; Hendrik Witt; Tong Lin; David J H Shih; Ben Ho; Mariarita Santi; Lyndsey Emery; Juliette Hukin; Christopher Dunham; Roger E McLendon; Eric S Lipp; Sridharan Gururangan; Andrew Grossbach; Pim French; Johan M Kros; Marie Lise C van Veelen; Amulya Nageswara N Rao; Caterina Giannini; Sarah Leary; Shin Jung; Claudia C Faria; Jaume Mora; Ulrich Schueller; Marta M Alonso; Jennifer A Chan; Almos Klekner; Lola B Chambless; Eugene I Hwang; Maura Massimino; Charles G Eberhart; Matthias A Karajannis; Benjamin Lu; Linda M Liau; Massimo Zollo; Veronica Ferrucci; Carlos Carlotti; Daniela P C Tirapelli; Uri Tabori; Eric Bouffet; Marina Ryzhova; David W Ellison; Thomas E Merchant; Mark R Gilbert; Terri S Armstrong; Andrey Korshunov; Stefan M Pfister; Michael D Taylor; Kenneth Aldape; Kristian W Pajtler; Marcel Kool; Vijay Ramaswamy; ...More
PUBLISHED: 2018, SOURCE: ACTA NEUROPATHOLOGICA, VOLUME: 136, ISSUE: 2
INDEXED IN: Scopus WOS
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TITLE: A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: A retrospective cohort study
AUTHORS: Pedro Castelo Branco; Ricardo Leao; Tatiana Lipman; Brittany Campbell; Donghyun Lee; Aryeh Price; Cindy Zhang; Abolfazl Heidari; Derek Stephens; Stefan Boerno; Hugo Coelho; Ana Gomes; Celia Domingos; Joana D Apolonio; Georg Schaefer; Robert G Bristow; Michal R Schweiger; Robert Hamilton; Alexandre Zlotta; Arnaldo Figueiredo; Helmut Klocker; Holger Sueltmann; Uri Tabori; ...More
PUBLISHED: 2016, SOURCE: ONCOTARGET, VOLUME: 7, ISSUE: 36
INDEXED IN: Scopus WOS
7
TITLE: BRAF Mutation and CDKN2A Deletion Define a Clinically Distinct Subgroup of Childhood Secondary High-Grade Glioma
AUTHORS: Matthew Mistry; Nataliya Zhukova; Daniele Merico; Patricia Rakopoulos; Rahul Krishnatry; Mary Shago; James Stavropoulos; Noa Alon; Jason D Pole; Peter N Ray; Vilma Navickiene; Joshua Mangerel; Marc Remke; Pawel Buczkowicz; Vijay Ramaswamy; Ana Guerreiro Stucklin; Martin Li; Edwin J Young; Cindy Zhang; Pedro Castelo Branco; Doua Bakry; Suzanne Laughlin; Adam Shlien; Jennifer Chan; Keith L Ligon; James T Rutka; Peter B Dirks; Michael D Taylor; Mark Greenberg; David Malkin; Annie Huang; Eric Bouffet; Cynthia E Hawkins; Uri Tabori; ...More
PUBLISHED: 2015, SOURCE: JOURNAL OF CLINICAL ONCOLOGY, VOLUME: 33, ISSUE: 9
INDEXED IN: Scopus WOS CrossRef
8
TITLE: Cytogenetic Prognostication Within Medulloblastoma Subgroups
AUTHORS: David J H Shih; Paul A Northcott; Marc Remke; Andrey Korshunov; Vijay Ramaswamy; Marcel Kool; Betty Luu; Yuan Yao; Xin Wang; Adrian M Dubuc; Livia Garzia; John Peacock; Stephen C Mack; Xiaochong C Wu; Adi Rolider; Sorana S Morrissy; Florence M G Cavalli; David T W Jones; Karel Zitterbart; Claudia C Faria; Ulrich Schueller; Leos Kren; Toshihiro Kumabe; Teiji Tominaga; Young Shin Ra; Miklos Garami; Peter Hauser; Jennifer A Chan; Shenandoah Robinson; Laszlo Bognar; Almos Klekner; Ali G Saad; Linda M Liau; Steffen Albrecht; Adam Fontebasso; Giuseppe Cinalli; Pasqualino De Antonellis; Massimo Zollo; Michael K Cooper; Reid C Thompson; Simon Bailey; Janet C Lindsey; Concezio Di Rocco; Luca Massimi; Erna M C Michiels; Stephen W Scherer; Joanna J Phillips; Nalin Gupta; Xing Fan; Karin M Muraszko; Rajeev Vibhakar; Charles G Eberhart; Maryam Fouladi; Boleslaw Lach; Shin Jung; Robert J Wechsler Reya; Michelle Fevre Montange; Anne Jouvet; Nada Jabado; Ian F Pollack; William A Weiss; Ji Yeoun Lee; Byung Kyu Cho; Seung Ki Kim; Kyu Chang Wang; Jeffrey R Leonard; Joshua B Rubin; Carmen de Torres; Cinzia Lavarino; Jaume Mora; Yoon Jae Cho; Uri Tabori; James M Olson; Amar Gajjar; Roger J Packer; Stefan Rutkowski; Scott L Pomeroy; Pim J French; Nanne K Kloosterhof; Johan M Kros; Erwin G Van Meir; Steven C Clifford; Franck Bourdeaut; Olivier Delattre; Francois F Doz; Cynthia E Hawkins; David Malkin; Wieslawa A Grajkowska; Marta Perek Polnik; Eric Bouffet; James T Rutka; Stefan M Pfister; Michael D Taylor; ...More
PUBLISHED: 2014, SOURCE: JOURNAL OF CLINICAL ONCOLOGY, VOLUME: 32, ISSUE: 9
INDEXED IN: Scopus WOS CrossRef
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TITLE: Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors  Full Text
AUTHORS: Joshua Mangerel; Aryeh Price; Pedro Castelo Branco; Jack Brzezinski; Pawel Buczkowicz; Patricia Rakopoulos; Diana Merino; Berivan Baskin; Jonathan Wasserman; Matthew Mistry; Mark Barszczyk; Daniel Picard; Stephen Mack; Marc Remke; Hava Starkman; Cynthia Elizabeth; Cindy Zhang; Noa Alon; Jodi Lees; Irene L Andrulis; Jay S Wunder; Nada Jabado; Donna L Johnston; James T Rutka; Peter B Dirks; Eric Bouffet; Michael D Taylor; Annie Huang; David Malkin; Cynthia Hawkins; Uri Tabori; ...More
PUBLISHED: 2014, SOURCE: ACTA NEUROPATHOLOGICA, VOLUME: 128, ISSUE: 6
INDEXED IN: Scopus WOS CrossRef
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TITLE: Telomerase inhibition abolishes the tumorigenicity of pediatric ependymoma tumor-initiating cells  Full Text
AUTHORS: Mark Barszczyk; Pawel Buczkowicz; Pedro Castelo Branco; Stephen C Mack; Vijay Ramaswamy; Joshua Mangerel; Sameer Agnihotri; Marc Remke; Brian Golbourn; Sanja Pajovic; Cynthia Elizabeth; Man Yu; Betty Luu; Andrew Morrison; Jennifer Adamski; Kathleen Nethery Brokx; Xiao Nan Li; Timothy Van Meter; Peter B Dirks; James T Rutka; Michael D Taylor; Uri Tabori; Cynthia Hawkins; ...More
PUBLISHED: 2014, SOURCE: ACTA NEUROPATHOLOGICA, VOLUME: 128, ISSUE: 6
INDEXED IN: Scopus WOS CrossRef
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