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TITLE: Wnt Signaling Regulates the Lineage Differentiation Potential of Mouse Embryonic Stem Cells through Tcf3 Down-Regulation  Full Text
AUTHORS: Yaser Atlasi; Rubina Noori; Claudia Gaspar ; Patrick Franken; Andrea Sacchetti; Haleh Rafati; Tokameh Mahmoudi; Charles Decraene; George A Calin; Bradley J Merrill; Riccardo Fodde;
PUBLISHED: 2013, SOURCE: PLOS GENETICS, VOLUME: 9, ISSUE: 5
INDEXED IN: Scopus WOS CrossRef
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TITLE: Colorectal Cancers Show Distinct Mutation Spectra in Members of the Canonical WNT Signaling Pathway According to Their Anatomical Location and Type of Genetic Instability  Full Text
AUTHORS: Cristina Albuquerque; Celia Baltazar; Bruno Filipe; Filipa Penha; Teresa Pereira; Ron Smits; Marilia Cravo ; Pedro Lage; Paulo Fidalgo; Isabel Claro; Paula Rodrigues; Isabel Veiga; Jose Silva Ramos; Isabel Fonseca; Carlos Nobre Leitao; Riccardo Fodde;
PUBLISHED: 2010, SOURCE: GENES CHROMOSOMES & CANCER, VOLUME: 49, ISSUE: 8
INDEXED IN: Scopus WOS CrossRef
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TITLE: A Targeted Constitutive Mutation in the Apc Tumor Suppressor Gene Underlies Mammary But Not Intestinal Tumorigenesis  Full Text
AUTHORS: Claudia Gaspar; Patrick Franken; Lia Molenaar; Cor Breukel; Martin van der Valk; Ron Smits; Riccardo Fodde;
PUBLISHED: 2009, SOURCE: PLOS GENETICS, VOLUME: 5, ISSUE: 7
INDEXED IN: Scopus WOS CrossRef
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TITLE: Cross-species comparison of human and mouse intestinal polyps reveals conserved mechanisms in adenomatous polyposis coli (APC)-driven tumorigenesis
AUTHORS: Claudia Gaspar; Joana Cardoso; Patrick Franken; Lia Molenaar; Hans Morreau; Gabriela Moeslein; Julian Sampson; Judith M Boer; Renee X de Menezes; Riccardo Fodde;
PUBLISHED: 2008, SOURCE: AMERICAN JOURNAL OF PATHOLOGY, VOLUME: 172, ISSUE: 5
INDEXED IN: Scopus WOS CrossRef
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TITLE: cAMP/PKA pathway activation in human mesenchymal stem cells in vitro results in robust bone formation in vivo
AUTHORS: Ramakrishnaiah Siddappa; Anton Martens; Joyce Doorn; Anouk Leusink; Cristina Olivo; Ruud Licht; Linda van Rijn; Claudia Gaspar; Riccardo Fodde; Frank Janssen; Clemens van Blitterswijk; Jan de Boer;
PUBLISHED: 2008, SOURCE: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, VOLUME: 105, ISSUE: 20
INDEXED IN: Scopus WOS CrossRef
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TITLE: APC dosage effects in tumorigenesis and stem cell differentiation
AUTHORS: Gaspar, C; Fodde, R;
PUBLISHED: 2004, SOURCE: INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY, VOLUME: 48, ISSUE: 5-6
INDEXED IN: Scopus WOS CrossRef
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TITLE: The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade
AUTHORS: Albuquerque, C; Breukel, C; van der Luijt, R; Fidalgo, P; Lage, P; Slors, FJM; Leitao, CN; Fodde, R; Smits, R;
PUBLISHED: 2002, SOURCE: HUMAN MOLECULAR GENETICS, VOLUME: 11, ISSUE: 13
INDEXED IN: Scopus WOS CrossRef
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TITLE: Somatic Apc mutations are selected upon their capacity to inactivate the beta-catenin downregulating activity  Full Text
AUTHORS: Smits, R; Hofland, N; Edelmann, W; Geugien, M; Jagmohan Changur, S; Albuquerque, C; Breukel, C; Kucherlapati, R; Kielman, MF; Fodde, R;
PUBLISHED: 2000, SOURCE: GENES CHROMOSOMES & CANCER, VOLUME: 29, ISSUE: 3
INDEXED IN: Scopus WOS CrossRef
9
TITLE: Detection of mutations in mismatch repair genes in Portuguese families with hereditary non-polyposis colorectal cancer (HNPCC) by a multi-method approach  Full Text
AUTHORS: Fidalgo, P; Almeida, MR; West, S; Gaspar, C; Maia, L; Wijnen, J; Albuquerque, C; Curtis, A; Cravo, M ; Fodde, R; Leitao, CN; Burn, J;
PUBLISHED: 2000, SOURCE: EUROPEAN JOURNAL OF HUMAN GENETICS, VOLUME: 8, ISSUE: 1
INDEXED IN: Scopus WOS CrossRef