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TITLE: Influence of polar side chains modifications on the dual enkephalinase inhibitory activity and conformation of human opiorphin, a pain perception related peptide  Full Text
AUTHORS: Monica Rosa; Filipa Marcelo; Luis P Calle; Catherine Rougeot; Jesus Jimenez Barbero; Gemma Arsequell; Gregorio Valencia;
PUBLISHED: 2015, SOURCE: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, VOLUME: 25, ISSUE: 22
INDEXED IN: Scopus WOS CrossRef
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TITLE: Structure-Activity Relationship Study of Opiorphin, a Human Dual Ectopeptidase Inhibitor with Antinociceptive Properties  Full Text
AUTHORS: Monica Rosa; Gemma Arsequell; Catherine Rougeot; Luis P Calle; Filipa Marcelo ; Marta Pinto; Nuria B Centeno; Jesus Jimenez Barbero; Gregorio Valencia;
PUBLISHED: 2012, SOURCE: JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 55, ISSUE: 3
INDEXED IN: Scopus WOS CrossRef
3
TITLE: Synthesis, biological evaluation and structural characterization of novel glycopeptide analogues of nociceptin N/OFQ  Full Text
AUTHORS: Gemma Arsequell; Monica Rosa; Carlos Mayato; Rosa L Dorta; Veronica Gonzalez Nunez; Katherine Barreto Valer; Filipa Marcelo ; Luis P Calle; Jesus T Vazquez; Raquel E Rodriguez; Jesus Jimenez Barbero; Gregorio Valencia;
PUBLISHED: 2011, SOURCE: ORGANIC & BIOMOLECULAR CHEMISTRY, VOLUME: 9, ISSUE: 17
INDEXED IN: Scopus WOS CrossRef
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TITLE: Isatin derivatives, a novel class of transthyretin fibrillogenesis inhibitors  Full Text
AUTHORS: Gonzalez, A; Quirante, J; Nieto, J; Almeida, MR ; Saraiva, MJ ; Planas, A; Arsequell, G; Valencia, G;
PUBLISHED: 2009, SOURCE: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, VOLUME: 19, ISSUE: 17
INDEXED IN: Scopus WOS CrossRef: 33
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TITLE: Iodine Atoms: A New Molecular Feature for the Design of Potent Transthyretin Fibrillogenesis Inhibitors  Full Text
AUTHORS: Teresa Mairal; Joan Nieto; Marta Pinto; Maria Rosario Almeida ; Luis Gales ; Alfredo Ballesteros; Jose Barluenga; Juan J Perez; Jesus T Vazquez; Nuria B Centeno; Maria Joao Saraiva ; Ana M Damas ; Antoni Planas; Gemma Arsequell; Gregorio Valencia;
PUBLISHED: 2009, SOURCE: PLOS ONE, VOLUME: 4, ISSUE: 1
INDEXED IN: Scopus WOS CrossRef: 46
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TITLE: Iodination of salicylic acid improves its binding to transthyretin  Full Text
AUTHORS: Luis Gales ; Maria Rosario Almeida ; Gemma Arsequell; Gregorio Valencia; Maria Joao Saraiva ; Ana Margarida Damas ;
PUBLISHED: 2008, SOURCE: BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, VOLUME: 1784, ISSUE: 3
INDEXED IN: Scopus WOS CrossRef: 14
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TITLE: Crystal Structure of Human Transthyretin in Complex with Iodo-Diflunisal, a Potent Amyloid Inhibitor.
AUTHORS: Gales, L ; Macedo Ribeiro, S; Arsequell, G; Valencia, G; Saraiva, MJ; Damas, AM;
PUBLISHED: 2004, SOURCE: ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, VOLUME: 60
INDEXED IN: WOS