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TITLE: Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1 Full Text
AUTHORS: Pöhner, I; Quotadamo, A; Panecka Hofman, J; Luciani, R; Santucci, M; Linciano, P; Landi, G; Di Pisa, F; Dello Iacono, L; Pozzi, C; Mangani, S; Gul, S; Witt, G; Ellinger, B; Kuzikov, M; Santarem, N; Cordeiro Da Silva, A ; Costi, MP; Venturelli, A; Wade, RC;
PUBLISHED: 2022, SOURCE: Journal of Medicinal Chemistry, VOLUME: 65, ISSUE: 13

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TITLE: Multitarget, Selective Compound Design Yields Potent Inhibitors of a Kinetoplastid Pteridine Reductase 1 Full Text
AUTHORS: Poehner, Ina; Quotadamo, Antonio; Panecka Hofman, Joanna; Luciani, Rosaria; Santucci, Matteo; Linciano, Pasquale; Landi, Giacomo; Di Pisa, Flavio; Dello Iacono, Lucia; Pozzi, Cecilia; Mangani, Stefano; Gul, Sheraz; Witt, Gesa; Ellinger, Bernhard; Kuzikov, Maria; Santarem, Nuno; Cordeiro da Silva, Anabela; Costi, Maria P.; Venturelli, Alberto; Wade, Rebecca C.;
PUBLISHED: 2022, SOURCE: JOURNAL OF MEDICINAL CHEMISTRY

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TITLE: Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform
AUTHORS: Carolina B Moraes; Gesa Witt; Maria Kuzikov; Bernhard Ellinper; Theodora Calogeropoulou; Kyriakos C Prousis; Stefano Mangani; Flavio Di Pisa; Giacomo Landi; Lucia Dello Lacono; Cecilia Pozzi; Lucio H Freitas Junior; Bruno dos Santos Pascoalino; Claudia P Bertolacini; Birte Behrens; Oliver Keminer; Jennifer Leu; Markus Wolf; Jeanette Reinshagen; Anabela Cordeiro da Silva ; Nuno Santarem; Alberto Venturelli; Stephen Wrigley; Deepa Karunakaran; Bethlehem Kebede; Ina Poehner; Wolfgang Mueller; Joanna Panecka Hofman; Rebecca C Wade; Martina Fenske; Joachim Clos; Jose M Maria Alunda; Maria J Jesus Corral; Elisa Uliassi; Maria Laura Bolognesi; Pasquale Linciano; Antonio Quotadamo; Stefania Ferrari; Matteo Santucci; Chiara Borsari; Maria Paola Costi; Sheraz Gul; ...More
PUBLISHED: 2019, SOURCE: SLAS DISCOVERY, VOLUME: 24, ISSUE: 3

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TITLE: Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections Full Text
AUTHORS: Pasquale Linciano; Cecilia Pozzi; Lucia dello Iacono; Flavio di Pisa; Giacomo Landi; Alessio Bonucci; Sheraz Gul; Maria Kuzikov; Bernhard Ellinger; Gesa Witt; Nuno Santarem; Catarina Baptista; Caio Franco; Carolina B Moraes; Wolfgang Mueller; Ulrike Wittig; Rosaria Luciani; Antony Sesenna; Antonio Quotadamo; Stefania Ferrari; Ina Pohner; Anabela Cordeiro da Silva ; Stefano Mangani; Luca Costantino; Maria Paola Costi; ...More
PUBLISHED: 2019, SOURCE: JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 62, ISSUE: 8

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TITLE: Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity Full Text
AUTHORS: Flavio Di Pisa; Giacomo Landi; Lucia Dello Iacono; Cecilia Pozzi; Chiara Borsari; Stefania Ferrari; Matteo Santucci; Nuno Santarem; Anabela Cordeiro da Silva ; Carolina B Moraes; Laura M Alcantara; Vanessa Fontana; Lucio H Freitas Junior; Sheraz Gul; Maria Kuzikov; Birte Behrens; Ina Poehner; Rebecca C Wade; Maria Paola Costi; Stefano Mangani;
PUBLISHED: 2017, SOURCE: MOLECULES, VOLUME: 22, ISSUE: 3

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TITLE: Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
AUTHORS: Linciano, P; Dawson, A; Pohner, I; Costa, DM; Sa, MS; Cordeiro da Silva, A ; Luciani, R; Gul, S; Witt, G; Ellinger, B; Kuzikov, M; Gribbon, P; Reinshagen, J; Wolf, M; Behrens, B; Hannaert, V; Michels, PAM; Nerini, E; Pozzi, C; di Pisa, F; Landi, G; Santarem, N; Ferrari, S; Saxena, P; Lazzari, S; Cannazza, G; Freitas, LH; Moraes, CB; Pascoalino, BS; Alcantara, LM; Bertolacini, CP; Fontana, V; Wittig, U; Muller, W; Wade, RC; Hunter, WN; Mangani, S; Costantino, L; Costi, MP; ...More
PUBLISHED: 2017, SOURCE: ACS OMEGA, VOLUME: 2, ISSUE: 9

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