ProfileOfResearchers

Identified 16

TITLE: Interleukin-7 receptor alpha mutational activation can initiate precursor B-cell acute lymphoblastic leukemia
AUTHORS: Almeida, ARM; Neto, JL; Cachucho, A; Euzebio, M; Meng, XY; Kim, R; Fernandes, MB; Raposo, B; Oliveira, ML; Ribeiro, D; Fragoso, R; Zenatti, PP; Soares, T; de Matos, MR; Correa, JR; Duque, M; Roberts, KG; Gu, ZH; Qu, CX; Pereira, C; Pyne, S; Pyne, NJ; Barreto, VM; Bernard Pierrot, I; Clappier, E; Mullighan, CG; Grosso, AR; Yunes, JA; Barata, JT; ...More
PUBLISHED: 2021, SOURCE: NATURE COMMUNICATIONS, VOLUME: 12, ISSUE: 1

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TITLE: NRARP displays either pro- or anti-tumoral roles in T-cell acute lymphoblastic leukemia depending on Notch and Wnt signaling
AUTHORS: Pinto, I; Duque, M; Goncalves, J; Akkapeddi, P; Oliveira, ML; Cabrita, R; Yunes, JA; Durum, SK; Barata, JT; Fragoso, R;
PUBLISHED: 2020, SOURCE: ONCOGENE, VOLUME: 39, ISSUE: 5

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TITLE: The Mir181ab1 cluster promotes KRAS-driven oncogenesis and progression in lung and pancreas
AUTHORS: Karmele Valencia; Oihane Erice; Kaja Kostyrko; Simone Hausmann; Elizabeth Guruceaga; Anuradha Tathireddy; Natasha M Flores; Leanne C Sayles; Alex G Lee; Rita Fragoso; Tian-Qiang Sun; Adrian Vallejo; Marta Roman; Rodrigo Entrialgo-Cadierno; Itziar Migueliz; Nerea Razquin; Puri Fortes; Fernando Lecanda; Jun Lu; Mariano Ponz-Sarvise; Chang-Zheng Chen; Pawel K Mazur; Alejandro A Sweet-Cordero; Silvestre Vicent; ...More
PUBLISHED: 2020, SOURCE: Journal of Clinical Investigation, VOLUME: 130, ISSUE: 4

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TITLE: A fully human anti-IL-7Rα antibody promotes antitumor activity against T-cell acute lymphoblastic leukemia
AUTHORS: Akkapeddi, P; Fragoso, R; Hixon, JA; Ramalho, AS; Oliveira, ML; Carvalho, T; Gloger, A; Matasci, M; Corzana, F; Durum, SK; Neri, D; Bernardes, GJL; Barata, JT;
PUBLISHED: 2019, SOURCE: Leukemia, VOLUME: 33, ISSUE: 9

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TITLE: Phosphatidylinositol 3-kinase inhibition potentiates glucocorticoid response in B-cell acute lymphoblastic leukemia
AUTHORS: Cecilia Evangelisti; Alessandra Cappellini; Mariana Oliveira; Rita Fragoso; João T Barata; Alice Bertaina; Franco Locatelli; Carolina Simioni; Luca M Neri; Francesca Chiarini; Annalisa Lonetti; Francesca Buontempo; Ester Orsini; Andrea Pession; Lucia Manzoli; Alberto Maria Martelli; Camilla Evangelisti;
PUBLISHED: 2018, SOURCE: Journal of Cellular Physiology, VOLUME: 233, ISSUE: 3

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TITLE: From the outside, from within: Biological and therapeutic relevance of signal transduction in T-cell acute lymphoblastic leukemia
AUTHORS: Oliveira, ML; Akkapeddi, P; Alcobia, I; Almeida, AR; Cardoso, BA; Fragoso, R; Serafim, TL; Barata, JT;
PUBLISHED: 2017, SOURCE: CELLULAR SIGNALLING, VOLUME: 38

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TITLE: PTEN and leukemia stem cells Full Text
AUTHORS: Fragoso, R; Barata, JT;
PUBLISHED: 2014, SOURCE: Advances in Biological Regulation, VOLUME: 56

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TITLE: Regulation of immune responses and tolerance: the microRNA perspective
AUTHORS: Chang‐Zheng Chen; Steven Schaffert; Rita Fragoso; Christina Loh;
PUBLISHED: 2013, SOURCE: Immunological Reviews, VOLUME: 253, ISSUE: 1

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TITLE: Modulating the Strength and Threshold of NOTCH Oncogenic Signals by mir-181a-1/b-1 Full Text
AUTHORS: Fragoso, R; Mao, T; Wang, S; Schaffert, S; Gong, X; Yue, S; Luong, R; Min, H; Yashiro Ohtani, Y; Davis, M; Pear, W; Chen, CZ;
PUBLISHED: 2012, SOURCE: PLoS Genetics, VOLUME: 8, ISSUE: 8

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