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TITLE: Plasma amyloid beta X-42/X-40 ratio and cognitive decline in suspected early and preclinical Alzheimer's disease  Full Text
AUTHORS: Vogelgsang, Jonathan; Hansen, Niels; Stark, Melina; Wagner, Michael; Klafki, Hans; Morgado, Barbara Marcos; Jahn Brodmann, Anke; Schott, Bjoern; Esselmann, Hermann; Bauer, Chris; Schuchhardt, Johannes; Kleineidam, Luca; Wolfsgruber, Steffen; Peters, Oliver; Schneider, Luisa Sophie; Wang, Xiao; Menne, Felix; Priller, Josef; Spruth, Eike; Altenstein, Slawek; Lohse, Andrea; Schneider, Anja; Fliessbach, Klaus; Vogt, Ina; Bartels, Claudia; Jessen, Frank; Rostamzadeh, Ayda; Duezel, Emrah; Glanz, Wenzel; Incesoy, Enise; Butryn, Michaela; Buerger, Katharina; Janowitz, Daniel; Ewers, Michael; Perneczky, Robert; Rauchmann, Boris; Guersel, Selim; Teipel, Stefan; Kilimann, Ingo; Goerss, Doreen; Laske, Christoph; Munk, Matthias; Sanzenbacher, Carolin; Spottke, Annika; Roy Kluth, Nina; Heneka, Michael; Brosseron, Frederic; Ramierez, Alfredo; Schmid, Matthias; Wiltfang, Jens; ...More
PUBLISHED: 2024, SOURCE: ALZHEIMERS & DEMENTIA
INDEXED IN: Scopus WOS
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TITLE: Diagnostic performance of automated plasma amyloid-beta assays combined with pre-analytical immunoprecipitation  Full Text
AUTHORS: Klafki, Hans W; Vogelgsang, Jonathan; Manuilova, Ekaterina; Bauer, Chris; Jethwa, Alexander; Esselmann, Hermann; Jahn Brodmann, Anke; Osterloh, Dirk; Lachmann, Ingolf; Breitling, Benedict; Rauter, Carolin; Hansen, Niels; Bouter, Caroline; Palme, Stefan; Schuchhardt, Johannes; Wiltfang, Jens;
PUBLISHED: 2022, SOURCE: ALZHEIMERS RESEARCH & THERAPY, VOLUME: 14, ISSUE: 1
INDEXED IN: Scopus WOS
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TITLE: Is plasma amyloid-beta 1-42/1-40 a better biomarker for Alzheimer's disease than A beta X-42/X-40?  Full Text
AUTHORS: Klafki, Hans Wolfgang; Morgado, Barbara; Wirths, Oliver; Jahn, Olaf; Bauer, Chris; Esselmann, Hermann; Schuchhardt, Johannes; Wiltfang, Jens;
PUBLISHED: 2022, SOURCE: FLUIDS AND BARRIERS OF THE CNS, VOLUME: 19, ISSUE: 1
INDEXED IN: WOS
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TITLE: The Role of Cathepsin B in the Degradation of A beta and in the Production of A beta Peptides Starting With Ala2 in Cultured Astrocytes  Full Text
AUTHORS: Oberstein, TJ; Utz, J; Spitzer, P; Klafki, HW; Wiltfang, J; Lewczuk, P; Kornhuber, J; Maler, JM;
PUBLISHED: 2021, SOURCE: FRONTIERS IN MOLECULAR NEUROSCIENCE, VOLUME: 13
INDEXED IN: Scopus WOS
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TITLE: Evaluation of cerebrospinal fluid glycoprotein NMB (GPNMB) as a potential biomarker for Alzheimer's disease  Full Text
AUTHORS: Aichholzer, F; Klafki, HW; Ogorek, I; Vogelgsang, J; Wiltfang, J; Scherbaum, N; Weggen, S; Wirths, O;
PUBLISHED: 2021, SOURCE: ALZHEIMERS RESEARCH & THERAPY, VOLUME: 13, ISSUE: 1
INDEXED IN: Scopus WOS
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TITLE: N-terminal heterogeneity of parenchymal and vascular amyloid-beta deposits in Alzheimer's disease  Full Text
AUTHORS: Zampar, S; Klafki, HW; Sritharen, K; Bayer, TA; Wiltfang, J; Rostagno, A; Ghiso, J; Miles, LA; Wirths, O;
PUBLISHED: 2020, SOURCE: NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
INDEXED IN: Scopus WOS
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TITLE: Development and Technical Validation of an Immunoassay for the Detection of APP(669-711) (A beta(-3-40)) in Biological Samples  Full Text
AUTHORS: Hans W Klafki; Petra Rieper; Anja Matzen; Silvia Zampar; Oliver Wirths; Jonathan Vogelgsang; Dirk Osterloh; Lara Rohdenburg; Timo J Oberstein; Olaf Jahn; Isaak Beyer; Ingolf Lachmann; Hans Joachim Knoelker; Jens Wiltfang;
PUBLISHED: 2020, SOURCE: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, VOLUME: 21, ISSUE: 18
INDEXED IN: Scopus WOS
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TITLE: A two-step immunoassay for the simultaneous assessment of A38, A40 and A42 in human blood plasma supports the A42/A40 ratio as a promising biomarker candidate of Alzheimer's disease  Full Text
AUTHORS: Hedieh Shahpasand Kroner; Hans W Klafki; Chris Bauer; Johannes Schuchhardt; Melanie Huettenrauch; Martina Stazi; Caroline Bouter; Oliver Wirths; Jonathan Vogelgsang; Jens Wiltfang;
PUBLISHED: 2018, SOURCE: ALZHEIMERS RESEARCH & THERAPY, VOLUME: 10, ISSUE: 1
INDEXED IN: Scopus WOS