1
TITLE: Unexpected rearrangement of ivermectin in the synthesis of new derivatives with trypanocidal and antiplasmodial activities  Full Text
AUTHORS: Sulik, Michal; Fontinha, Diana; Steverding, Dietmar; Sobczak, Szymon; Antoszczak, Michal; Prudencio, Miguel; Huczynski, Adam;
PUBLISHED: 2024, SOURCE: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 263
INDEXED IN: Scopus WOS
2
TITLE: New 4-(N-cinnamoylbutyl)aminoacridines as potential multi-stage antiplasmodial leads  Full Text
AUTHORS: Fonte, Melanie; Fontinha, Diana; Moita, Diana; Cano Prades, Omar; Avalos Padilla, Yunuen; Fernandez Busquets, Xavier; Prudencio, Miguel; Paula Gomes ; Teixeira, Catia ;
PUBLISHED: 2023, SOURCE: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 258
INDEXED IN: Scopus WOS CrossRef
3
TITLE: Synthesis and antiplasmodial activity of regioisomers and epimers of second-generation dual acting ivermectin hybrids  Full Text
AUTHORS: Singh, L; Fontinha, D; Francisco, D; Prudencio, M; Singh, K;
PUBLISHED: 2022, SOURCE: SCIENTIFIC REPORTS, VOLUME: 12, ISSUE: 1
INDEXED IN: Scopus WOS CrossRef
4
TITLE: A Histone Deacetylase (HDAC) Inhibitor with Pleiotropic In Vitro Anti-Toxoplasma and Anti-Plasmodium Activities Controls Acute and Chronic Toxoplasma Infection in Mice  Full Text
AUTHORS: Jublot, Delphine; Cavailles, Pierre; Kamche, Salima; Francisco, Denise; Fontinha, Diana; Prudencio, Miguel; Guichou, Jean Francois; Labesse, Gilles; Sereno, Denis; Loeuillet, Corinne;
PUBLISHED: 2022, SOURCE: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, VOLUME: 23, ISSUE: 6
INDEXED IN: Scopus WOS CrossRef
5
TITLE: Discovery of spirooxadiazoline oxindoles with dual-stage antimalarial activity  Full Text
AUTHORS: Lopes, Elizabeth A.; Mestre, Raquel; Fontinha, Diana; Legac, Jenny; Pei, Jinxin, V; Sanches Vaz, Margarida; Mori, Mattia; Lehane, Adele M.; Rosenthal, Philip J.; Prudencio, Miguel; Santos, Maria M. M.;
PUBLISHED: 2022, SOURCE: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 236
INDEXED IN: Scopus WOS CrossRef
6
TITLE: Pre-erythrocytic Activity of M5717 in Monotherapy and Combination in Preclinical Plasmodium Infection Models
AUTHORS: Fontinha, Diana; Arez, Francisca; Gal, Isabella Ramella; Nogueira, Goncalo; Moita, Diana; Baeurle, Tobias Hyun Ho; Brito, Catarina; Spangenberg, Thomas; Alves, Paula M.; Prudencio, Miguel;
PUBLISHED: 2022, SOURCE: ACS INFECTIOUS DISEASES, VOLUME: 8, ISSUE: 4
INDEXED IN: Scopus WOS CrossRef
7
TITLE: A Hybrid of Amodiaquine and Primaquine Linked by Gold(I) Is a Multistage Antimalarial Agent Targeting Heme Detoxification and Thiol Redox Homeostasis  Full Text
AUTHORS: Pereira, Caroline De Souza; Quadros, Helenita Costa; Aboagye, Samuel Yaw; Fontinha, Diana; D'Alessandro, Sarah; Byrne, Margaret Elizabeth; Gendrot, Mathieu; Fonta, Isabelle; Mosnier, Joel; Moreira, Diogo Rodrigo M.; Basilico, Nicoletta; Williams, David. L. L.; Prudencio, Miguel; Pradines, Bruno; Navarro, Maribel;
PUBLISHED: 2022, SOURCE: PHARMACEUTICS, VOLUME: 14, ISSUE: 6
INDEXED IN: Scopus WOS CrossRef
8
TITLE: Spiro-beta-lactam BSS-730A Displays Potent Activity against HIV and Plasmodium
AUTHORS: Bartolo, I; Santos, BS; Fontinha, D; Machado, M; Francisco, D; Sepodes, B; Rocha, J; Mota Filipe, H; Pinto, R; Figueira, ME; Barroso, H; Nascimento, T; de Matos, APA; Alves, AJS; Alves, NG; Simoes, CJV; Prudencio, M; Melo, TMVDPE; Taveira, N;
PUBLISHED: 2021, SOURCE: ACS INFECTIOUS DISEASES, VOLUME: 7, ISSUE: 2
INDEXED IN: WOS
9
TITLE: Further investigation of harmicines as novel antiplasmodial agents: Synthesis, structure-activity relationship and insight into the mechanism of action  Full Text
AUTHORS: Marinovic, M; Poje, G; Perkovic, I; Fontinha, D; Prudencio, M; Held, J; de Carvalho, LP; Tandaric, T; Vianello, R; Rajic, Z;
PUBLISHED: 2021, SOURCE: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, VOLUME: 224
INDEXED IN: WOS
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TITLE: Studies of Potency and Efficacy of an Optimized Artemisinin-Quinoline Hybrid against Multiple Stages of the Plasmodium Life Cycle  Full Text
AUTHORS: Quadros, HC; Capci, A; Herrmann, L; D'Alessandro, S; Fontinha, D; Azevedo, R; Villarreal, W; Basilico, N; Prudencio, M; Tsogoeva, SB; Moreira, DRM;
PUBLISHED: 2021, SOURCE: PHARMACEUTICALS, VOLUME: 14, ISSUE: 11
INDEXED IN: Scopus WOS CrossRef
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