2
TÍTULO: Discovery of Novel Inhibitors of Uridine Diphosphate-N-Acetylenolpyruvylglucosamine Reductase (MurB) from Pseudomonas aeruginosa, an Opportunistic Infectious Agent Causing Death in Cystic Fibrosis Patients
AUTORES: Marta Acebrón-García-de-Eulate; Joan Mayol-Llinàs; Matthew T O Holland; So Yeon Kim; Karen P Brown; Chiara Marchetti; Jeannine Hess; Ornella Di Pietro; Vitor Mendes; Chris Abell; Andres A Floto; Anthony G Coyne; Tom L Blundell;
PUBLICAÇÃO: 2022, FONTE: Journal of Medicinal Chemistry, VOLUME: 65, NÚMERO: 3
INDEXADO EM: CrossRef: 5
NO MEU: ORCID
3
TÍTULO: Development of Inhibitors of SAICAR Synthetase (PurC) from Mycobacterium abscessus Using a Fragment-Based Approach
AUTORES: Sitthivut Charoensutthivarakul; Sherine E Thomas; Amy Curran; Karen P Brown; Juan M Belardinelli; Andrew J Whitehouse; Marta Acebrón-García-de-Eulate; Jaspar Sangan; Subramanian G Gramani; Mary Jackson; Vitor Mendes; Andres A Floto; Tom L Blundell; Anthony G Coyne; Chris Abell;
PUBLICAÇÃO: 2022, FONTE: ACS Infectious Diseases, VOLUME: 8, NÚMERO: 2
INDEXADO EM: CrossRef: 10
NO MEU: ORCID
4
TÍTULO: Structural Characterization of Mycobacterium abscessus Phosphopantetheine Adenylyl Transferase Ligand Interactions: Implications for Fragment-Based Drug Design
AUTORES: Sherine E Thomas; William J McCarthy; Jamal El Bakali; Karen P Brown; So Yeon Kim; Michal Blaszczyk; Vítor Mendes; Chris Abell; Andres A Floto; Anthony G Coyne; Tom L Blundell;
PUBLICAÇÃO: 2022, FONTE: Frontiers in Molecular Biosciences, VOLUME: 9
INDEXADO EM: CrossRef: 5
NO MEU: ORCID
5
TÍTULO: A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis
AUTORES: Pooja Gupta; Sherine E Thomas; Shaymaa A Zaidan; Maria A Pasillas; James Cory-Wright; Víctor Sebastián-Pérez; Ailidh Burgess; Emma Cattermole; Clio Meghir; Chris Abell; Anthony G Coyne; William R Jacobs; Tom L Blundell; Sangeeta Tiwari; Vítor Mendes;
PUBLICAÇÃO: 2021, FONTE: Computational and Structural Biotechnology Journal, VOLUME: 19
INDEXADO EM: CrossRef: 20
NO MEU: ORCID
6
TÍTULO: Targeting Mycobacterium tuberculosis CoaBC through Chemical Inhibition of 4′-Phosphopantothenoyl-l-cysteine Synthetase (CoaB) Activity
AUTORES: Joanna C Evans; Dinakaran Murugesan; John M Post; Vitor Mendes; Zhe Wang; Navid Nahiyaan; Sasha L Lynch; Stephen Thompson; Simon R Green; Peter C Ray; Jeannine Hess; Christina Spry; Anthony G Coyne; Chris Abell; Helena I M Boshoff; Paul G Wyatt; Kyu Y Rhee; Tom L Blundell; Clifton E Barry; Valerie Mizrahi;
PUBLICAÇÃO: 2021, FONTE: ACS Infectious Diseases, VOLUME: 7, NÚMERO: 6
INDEXADO EM: CrossRef: 4
NO MEU: ORCID
7
TÍTULO: Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site
AUTORES: Vitor Mendes; Simon R Green; Joanna C Evans; Jeannine Hess; Michal Blaszczyk; Christina Spry; Owain Bryant; James Cory-Wright; Daniel S-H Chan; Pedro H M Torres; Zhe Wang; Navid Nahiyaan; Sandra O’Neill; Sebastian Damerow; John Post; Tracy Bayliss; Sasha L Lynch; Anthony G Coyne; Peter C Ray; Chris Abell; Kyu Y Rhee; Helena I M Boshoff; Clifton E Barry; Valerie Mizrahi; Paul G Wyatt; Tom L Blundell; ...Mais
PUBLICAÇÃO: 2021, FONTE: Nature Communications, VOLUME: 12, NÚMERO: 1
INDEXADO EM: CrossRef: 9
NO MEU: ORCID
8
TÍTULO: Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors
AUTORES: Mohamad Sabbah; Vitor Mendes; Robert G Vistal; David M G Dias; Monika Záhorszká; Katarína Mikušová; Jana Korduláková; Anthony G Coyne; Tom L Blundell; Chris Abell;
PUBLICAÇÃO: 2020, FONTE: Journal of Medicinal Chemistry, VOLUME: 63, NÚMERO: 9
INDEXADO EM: CrossRef: 30
NO MEU: ORCID
9
TÍTULO: Correction to Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors
AUTORES: Mohamad Sabbah; Vitor Mendes; Robert G Vistal; David M G Dias; Monika Záhorszká; Katarína Mikušová; Jana Korduláková; Anthony G Coyne; Tom L Blundell; Chris Abell;
PUBLICAÇÃO: 2020, FONTE: Journal of Medicinal Chemistry, VOLUME: 63, NÚMERO: 15
INDEXADO EM: CrossRef
NO MEU: ORCID
10
TÍTULO: Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification
AUTORES: Sherine E Thomas; Andrew J Whitehouse; Karen Brown; Sophie Burbaud; Juan M Belardinelli; Jasper Sangen; Ramanuj Lahiri; Mark Daben J Libardo; Pooja Gupta; Sony Malhotra; Helena I M Boshoff; Mary Jackson; Chris Abell; Anthony G Coyne; Tom L Blundell; Rodrigo Andres Floto; Vítor Mendes;
PUBLICAÇÃO: 2020, FONTE: Nucleic Acids Research, VOLUME: 48, NÚMERO: 14
INDEXADO EM: CrossRef: 19
NO MEU: ORCID
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