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Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry

AuthID
P-00W-C8Q

Author(s)

Ferhati, X

Jimenez-Moreno, E

Hoyt, EA

Salluce, G

Cabeza-Cabrerizo, M

Salaverri, N

Martinez, A

Laserna, V

Jimenez-Oses, G

Tipo de Documento

Article

Year published

2022

Publicado

in JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN: 0002-7863

Volume: 144, Número: 12, Páginas: 5284-5294 (11)

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Publication Identifiers

DOI: 10.1021/jacs.1c07675

Pubmed: 35293206

SCOPUS: 2-s2.0-85127144077

Wos: WOS:000799109400014

Source Identifiers

ISSN: 0002-7863

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Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry

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Single Mutation on Trastuzumab Modulates the Stability of Antibody-Drug Conjugates Built Using Acetal-Based Linkers and Thiol-Maleimide Chemistry

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